Cardiovascular health and diabetes

Module 3: Cardiovascular outcomes in trials for the newer glucose-lowering therapies

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CME Credits: 1
Module duration: 1 hour
Launch date: Winter 2019 (version 1)
Updated: Summer 2022 (version 2)
Expiry date: March 2027
Audience: Cardiologists (Subspeciality), Diabetes and Metabolism Specialists (Subspeciality), Endocrinologists (Subspeciality), General Physicians (Subspeciality), Pharmacologists (Subspeciality)

The range of glucose-lowering drugs available to physicians has expanded greatly since the early landmark studies in this field. New regulations have also changed the way cardiovascular risk is factored into contemporary trial design. With these changes in mind, this module looks at the cardiovascular aspects of the outcomes from trials of the newer diabetes therapies.

Learning Outcomes

By the end of this module, you will be able to:

Explain the USA’s Food and Drug Administration’s (FDA) guidance on cardiovascular safety

Summarise the main cardiovascular outcome data for clinical trials of DPP-4 inhibitors, SGLT-2 inhibitors and GLP-1 receptor agonists

Discuss how the cardiovascular aspects of the outcomes from trials of the newer diabetes therapies will influence your clinical practice


This module includes self-marked assessments, such as knowledge checks and/or case studies, as well as a marked final assessment, which you can attempt up to five times. To complete the module, you must review all chapters, pass the final assessment (80% pass mark), and fill in our feedback form.


Contributors

Professor
Miles Fisher
Author
Professor
John Wilding
Expert Reviewer
Assessment Setter