In this module, Professor Lena Eliasson unpicks the complex pathway of events involved in exocytosis within the beta cell – which is critical to sustained insulin secretion in response to glucose. Then, in two additional sub-modules attached to this module, Professors Malin Fex and Erik Renström explore in more detail the roles played by mitochondria and calcium in the exocytotic process.
By the end of this module, you will be able to:
✓ Summarise the complex pathway of events involved in exocytosis within the beta cell critical to sustained insulin secretion in response to glucose
✓ Explain the role and importance of mitochondrial metabolism, calcium homeostasis and other circulating factors on beta cell metabolism and function
✓ Examine the links between the changes in exocytosis or exocytotic genes and the potential for a defect in exocytosis to contribute to the development of type 2 diabetes
This module includes self-marked assessments, such as knowledge checks and/or case studies, as well as a marked final assessment, which you can attempt up to five times. To complete the module, you must review all chapters, pass the final assessment (80% pass mark), and fill in our feedback form.