Cardiovascular health and diabetes

Module 4: The cardiovascular benefits of lowering cholesterol

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CME Credits: 1
Module duration: 1 hour
Launch date: Spring 2020 (version 1)
Updated: Summer 2022 (version 2)
Expiry date: March 2027
Audience: Cardiologists (Subspeciality), Diabetes and Metabolism Specialists (Subspeciality), Endocrinologists (Subspeciality), General Physicians (Subspeciality), Pharmacologists (Subspeciality), Public Health Physicians (Advanced)

Sabatine MS, Leiter LA, Wiviott SD, Giugliano RP, Deedwania P, De Ferrari GM, Murphy SA, Kuder JF, Gouni-Berthold I, Lewis BS, Handelsman Y, Pineda AL, Honarpour N, Keech AC, Sever PS, Pedersen TR. Cardiovascular safety and efficacy of the PCSK9 inhibitor evolocumab in patients with and without diabetes and the effect of evolocumab on glycaemia and risk of new-onset diabetes: a prespecified analysis of the FOURIER randomised controlled trial. Lancet Diabetes Endocrinol. 2017 Dec;5(12):941-950.
http://www.ncbi.nlm.nih.gov/pubmed/28927706

Learning Outcomes

By the end of this module, you will be able to:

Compare the three meta-analyses conducted by the Cholesterol Treatment Trialists’ (CTT) Collaboration in 2008, 2010 and 2016

Analyse the evidence underpinning the use of selective cholesterol-absorption inhibitors (i.e. ezetemibe), fibrates and PCSK9-inhibitors as lipid-lowering treatment for people with diabetes

Identify lipid-lowering treatment options for people with diabetes across different age groups


This module includes self-marked assessments, such as knowledge checks and/or case studies, as well as a marked final assessment, which you can attempt up to five times. To complete the module, you must review all chapters, pass the final assessment (80% pass mark), and fill in our feedback form.


Contributors

Professor
Miles Fisher
Author
Professor
John Wilding
Expert Reviewer
Assessment Setter