SGLT-2 inhibitors

Hello. I’m Miles Fisher. I’m a diabetologist at Glasgow Royal Infirmary and an Honorary Professor at the University of Glasgow. Heart failure and diabetes are common comorbidities. When you look at it from the heart failure perspective, about one-third of all patients with heart failure have diabetes and another third have impaired glucose tolerance, with only one-third having normal glucose tolerance. From the diabetes perspective, heart failure is now the single most common presenting feature for heart disease in people with diabetes. So, we need to have treatments that can potentially improve the outcome of both of these serious conditions.

Melanie J. Davies, Vanita R. Aroda, Billy S. Collins, Robert A. Gabbay, Jennifer Green, Nisa M. Maruthur, Sylvia E. Rosas, Stefano Del Prato, Chantal Mathieu, Geltrude Mingrone, Peter Rossing, Tsvetalina Tankova, Apostolos Tsapas, John B. Buse; Management of Hyperglycemia in Type 2 Diabetes, 2022. A Consensus Report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD). Diabetes Care 1 November 2022; 45 (11): 2753–2786.
http://doi.org/10.2337/dci22-0034