Non-alcoholic fatty liver disease

Module 2: NAFLD — prevention and treatment

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CME Credits: 2
Module duration: 2 hours
Launch date: Autumn 2021 (version 1)
Updated: -
Expiry date: March 2027

My name is Michael Roden. I’m a Professor of Endocrinology and Diabetology at Heinrich Heine University in Düsseldorf, Germany, and I’m also Director of the German Diabetes Centre, also in Düsseldorf, Germany. Today I will be talking about the treatment of people with non-alcoholic fatty liver disease (NAFLD), particularly in the context of type 2 diabetes.

This module examines the therapeutic options currently available to help prevent non-alcoholic fatty liver disease (NAFLD) and its progression in people with diabetes.

Joint EASL-EASD-EASO guidelines on the clinical management of NAFLD, Diabetologia. 2016;59(6):1148-1149.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861747/pdf/125_2016_Article_3941.pdf

Taylor R, Al-Mrabeh A, Zhyzhneuskaya S, Peters C, Barnes AC, Aribisala BS, Hollingsworth KG, Mathers JC, Sattar N, Lean M. Remission of Human Type 2 Diabetes Requires Decrease in Liver and Pancreas Fat Content but Is Dependent upon Capacity for β Cell Recovery. Cell Metab. 2018 Oct 2;28(4):547-556.e3.
https://pubmed.ncbi.nlm.nih.gov/30078554/

Learning Outcomes

By the end of this module, you will be able to:

Outline the potential benefits and limitations of lifestyle interventions on the prevention and treatment of NAFLD

Explain why interventions that result in significant and sustainable weight loss are so important to preventing NAFLD and its progression

Compare the potential uses of type 2 diabetes medications to treat NAFLD


This module includes self-marked assessments, such as knowledge checks and/or case studies, as well as a marked final assessment, which you can attempt up to five times. To complete the module, you must review all chapters, pass the final assessment (80% pass mark), and fill in our feedback form.


Contributors

Professor
Michael Roden
Author
Professor
Gianluca Perseghin
Expert Reviewer
Assessment Setter
Assessment Setter