5 things we don't yet know

Top diabetes researchers’ top 5 research questions.

Complications research

What are your most pressing questions about diabetes complications?

Optimising therapy

How might we treat patients with type 2 diabetes and kidney disease in the future?  

Towards a cure

The mysteries of beta cell failure and why the body makes a mistake in type 1 diabetes are among the unknowns that Pr...

On the move

Dr Jeremy Robles discusses the complex picture of diabetes and migration, and how research can help to untangle the q...

From the cell to the whole body

Professor Juleen Zierath details the unknowns that are yet to be solved by research, including how the organs work in...

Moving forward

Professor Dominik Pesta on the hot topics that need more research, including individualised exercise prescriptions fo...

Life-changing answers

Professor Stephanie Amiel outlines the areas she’d like to be better understood, including type 1 diabetes immunology...

A clearer picture

A definitive answer on metformin, more detail on SGLT-2 inhibitors and the best combinations of lipid-lowering drugs ...

Attention to detail

Professor Nisa Maruthur reflects on the unknowns around type 2 diabetes prevention, complications, pharmacotherapy an...

A hopeful future

The evolving field of diabetes subtypes, what is implied by adipose tissue being composed of several types of fat cel...

On the cusp

Understanding the full spectrum of immunotherapy techniques in type 1 diabetes, the optimal approach to the obesity p...

Longer lasting

How to make lifestyle interventions more durable and how to treat insulin resistance with more acceptable medications...

Pregnancy and beyond

The cut-off for first trimester diagnosis, breastfeeding, the use of metformin and the EMERGE trial are among the top...

A fuller understanding

Why lean, younger people are being diagnosed with type 2 diabetes and the impact of diet in gestational diabetes are ...

A brighter future

Biomarkers that tell us which patients are at higher risk of beta cell dysfunction, drugs that could cure it and what...

Tackling with tech

We don’t know enough about the common denominators that link chronic conditions – Professor Cees Tack discusses exact...

A deeper understanding

What we need to know about diabetes in people with severe mental illness as well as the psychosocial aspects of diabe...

Multiplicity mysteries

What’s the course of type 2 diabetes, how should we treat it and how can we prevent it? Listen to Professor Clifford ...

Within our reach

Exercise would be easier and more beneficial for people with type 1 diabetes if we could one day find the answers to ...

Polypharmacy in type 2 diabetes

Matching the right drugs to the right people, improving cardiovascular outcomes and reducing the burden of multiple m...

Preserve, predict, prevent

Professor Bruce Wolffenbuttel on his pick of the top five research questions that would benefit our understanding of ...

Replacement strategies

Availability, safety and prevention are high on Professor Eelco de Koning’s list of priorities for research into isle...

Screen and intervene

Earlier, more tailored interventions to prevent type 1 diabetes are high on the list of research priorities for Profe...

Questions of healing

What are the mechanisms involved in wound healing? How can emerging technologies help prevent ulceration? How cost-ef...

Get it together

Integration of care, behaviour change and how we’re going to pay for everything: hear the rest of Dr João Filipe Rap...

Obesity and diabetes

How does obesity accelerate the beta cell failure that’s characteristic of type 2 diabetes? And why does NAFLD advanc...

Mission remission

We now know that weight loss can result in type 2 diabetes remission, but questions remain. What is the effect of rem...

A growing problem

With the obesity crisis showing no signs of abating, insulin resistance in children and adolescents with type 1 diabe...

A big difference

Personalised immune modulation and technology for more exact carb counting are two of the research areas that would p...

Best foot forward

Better treatments for painful diabetic neuropathy, understanding the pathomechanisms of Charcot foot and the role of ...

Fasting unknowns

What is happening to blood sugars and hormones during Ramadan fasting? Can new technologies help us manage fasting mo...

Take heart

Should we combine modern drugs? What are ideal blood pressure targets? And why are women with diabetes at such high r...

Saline replacement?

Could an ideal fluid be created to replace saline and Ringer’s lactate? This and other questions about DKA management...

Transplant goals

Finding new sources of insulin-producing cells and reducing the burden of immunosuppression are among Professor Franc...

Opportunity awaits

The rising use of diabetes technologies opens up huge opportunities to deepen our knowledge. Professor Pratik Choudha...

Time will tell

GLP-1 receptor agonists have been researched for decades, but there’s still much to discover. Professor Filip Knop fr...

The earlier the better

Professor Tina Vilsbøll from the Steno Diabetes Center, Copenhagen, on why research should focus on the initial stage...

The next 10 years

What is causing the decline of beta-cell function in type 2 diabetes and is it possible to reverse it? And what is th...

Best foot forward

Professor Andrew Boulton on the five things we need to investigate to take forward research into diabetes and the foot.

Unsolved mysteries of diabetes and the kidney

Professor Sally Marshall’s pick of the top 5 things we don’t yet know about diabetic nephropathy.

Top 5 for type 1

Professor Chantal Mathieu on what we still need to learn about type 1 diabetes.

What we need to know about type 2

Kicking off a new series, where leading experts set out research priorities for their area of diabetes, Professor Ste...